METTL14 anticorps (AA 2-36)
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- Antigène Voir toutes METTL14 Anticorps
- METTL14 (Methyltransferase Like 14 (METTL14))
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Épitope
- AA 2-36
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp METTL14 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée (Details)
- Expected species reactivity: Bovine
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 2-36 from the N-terminal region of the human protein was used as the immunogen for the METTL14 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product METTL14 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting points. Titration of the METTL14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:2000
- Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the METTL14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- METTL14 (Methyltransferase Like 14 (METTL14))
- Autre désignation
- METTL14 (METTL14 Produits)
- Synonymes
- anticorps RGD1304822, anticorps G430022H21Rik, anticorps mKIAA1627, anticorps zgc:77296, anticorps methyltransferase like 14, anticorps methyltransferase like 14 L homeolog, anticorps Mettl14, anticorps mettl14.L, anticorps METTL14, anticorps mettl14
- Sujet
- N6-adenosine-methyltransferase subunit METTL14 is an N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.
- UniProt
- Q9HCE5
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