×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
R-Spondin 3 anticorps (AA 214-248)
RSPO3
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5647910
Détail du produit anti-R-Spondin 3 anticorps
(cache)
Antigène
Voir toutes R-Spondin 3 (RSPO3) Anticorps
R-Spondin 3 (RSPO3)
Épitope
Tous les épitopes à travers R-Spondin 3 Anticorps.
AA 214-248
Reactivité
Toutes les réactivités sur R-Spondin 3 Anticorps
Humain
Hôte
Toutes les hôtes sur R-Spondin 3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur R-Spondin 3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers R-Spondin 3 Anticorps
Cet anticorp R-Spondin 3 est non-conjugé
Application
Tous les applications à travers R-Spondin 3 Anticorps.
Western Blotting (WB)
Purification
Antigen affinity purified
Immunogène
A portion of amino acids 214-248 from the human protein was used as the immunogen for the RSPO3 antibody.
Isotype
Ig Fraction
Top Product
Discover our top product RSPO3 Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Western blot: 1:1000-2000
Restrictions
For Research Use only
Stockage
(cache)
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the RSPO3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Détails sur R-Spondin 3
(cache)
Antigène
R-Spondin 3 (RSPO3)
Autre désignation
RSPO3 / R-spondin 3 (RSPO3 Produits )
Synonymes
anticorps pwtsr, anticorps thsd2, anticorps cristin1, anticorps CRISTIN1, anticorps PWTSR, anticorps THSD2, anticorps RGD1563246, anticorps 2810459H04Rik, anticorps AW742308, anticorps Cristin1, anticorps Thsd2, anticorps R-spondin 3, anticorps rspo3, anticorps RSPO3, anticorps Rspo3
Sujet
R-spondin-3 is an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
ID gène
84870
UniProt
Q9BXY4
Vus récemment
(cache)