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BRMS1 anticorps (AA 1-246)

BRMS1 Reactivité: Humain WB, ELISA, IP Hôte: Souris Monoclonal 2D4-2G11 unconjugated
N° du produit ABIN565191
  • Antigène Voir toutes BRMS1 Anticorps
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Épitope
    • 15
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-246
    Reactivité
    • 53
    • 25
    • 24
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 1
    Souris
    Clonalité
    • 52
    • 1
    Monoclonal
    Conjugué
    • 22
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BRMS1 est non-conjugé
    Application
    • 46
    • 21
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Fonction
    Mouse monoclonal antibody raised against a full length recombinant BRMS1.
    Séquence
    MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAAVSPQK RKSDGP
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    BRMS1 (AAH09834, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2D4-2G11
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ventura, Quezada, Maloney, Fernandes, Antecka, Martins, Bakalian, di Cesare, Burnier: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." dans: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).

    Liu, Mayo, Nagji, Hall, Shock, Xiao, Stelow, Jones: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." dans: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).

    Cui, Liu, He, Li, Huang, Sun, Tang, Chen, Jiang, Chen, Yun, Zeng, Guo, Wang, Ma: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." dans: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).

    Kim, Nam, Pyo, Jang, Kim, Kim, Boo, Lee, Yoon, Baek, Kim: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." dans: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).

    Nagji, Liu, Stelow, Stukenborg, Jones: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." dans: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).

    Smith, Liu, Siefert, Moskaluk, Petroni, Jones: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." dans: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).

    Rivera, Megias, Bravo: "Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1." dans: Journal of proteome research, Vol. 6, Issue 10, pp. 4006-18, (2007) (PubMed).

    Liu, Smith, Jones: "Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis." dans: Molecular and cellular biology, Vol. 26, Issue 23, pp. 8683-96, (2006) (PubMed).

  • Antigène
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Autre désignation
    BRMS1 (BRMS1 Produits)
    Synonymes
    anticorps MGC98869, anticorps BRMS1, anticorps BRMS1L, anticorps AV003220, anticorps AW554636, anticorps si:zc188c22.3, anticorps si:zc194c5.2, anticorps wu:fb57b08, anticorps zgc:56414, anticorps breast cancer metastasis suppressor 1, anticorps breast cancer metastasis-suppressor 1, anticorps breast cancer metastasis suppressor 1 L homeolog, anticorps BRMS1, anticorps Brms1, anticorps brms1.L, anticorps brms1
    Sujet
    Full Gene Name: breast cancer metastasis suppressor 1
    Synonyms: DKFZp564A063
    ID gène
    25855
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