PDCD1LG2 anticorps (PE)
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- Antigène Voir toutes PDCD1LG2 Anticorps
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PDCD1LG2 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
- Réactivité croisée (Details)
- Human
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- human CD273 cDNA
- Clone
- 24F-10C12
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product PDCD1LG2 Anticorps primaire
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- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Commentaires
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- Autre désignation
- CD273 / PD-L2 (PDCD1LG2 Produits)
- Synonymes
- anticorps PDL2, anticorps B7DC, anticorps Btdc, anticorps CD273, anticorps PD-L2, anticorps PDCD1L2, anticorps bA574F11.2, anticorps B7-DC, anticorps F730015O22Rik, anticorps programmed cell death 1 ligand 2, anticorps PDCD1LG2, anticorps Pdcd1lg2
- Sujet
- Programmed cell death 1 ligand 2,CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.,PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, Butyrophilin, B7-DC,
- ID gène
- 80380
- UniProt
- Q9BQ51
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