Recombinant CD40L (Ruplizumab Biosimilar) anticorps
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- Antigène Tous les produits CD40L (Ruplizumab Biosimilar)
- CD40L (Ruplizumab Biosimilar)
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD40L (Ruplizumab Biosimilar) est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)
- Specificité
- The antibody binds to CD40L with an IC50 of 0.845 μg/mL.
- Attributs du produit
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- Purification
- Purified antibody.
- Pureté
- > 98 % as determined by SDS-PAGE
- niveau d'endotoxine
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogène
- Human CD40L
- Clone
- Hu5c8
- Isotype
- IgG kappa
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anti-CD40L (Ruplizumab Biosimilar) antibody
Reactivité: Humain FACS, WB, BR Hôte: Human Monoclonal hu5c8 unconjugated Recombinant Antibody
anti-CD40L (Ruplizumab Biosimilar) antibodyResearch Grade Reactivité: Humain FACS, ELISA Hôte: Humanized Monoclonal unconjugated Recombinant Antibody
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- Indications d'application
- The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531? ±?155 hours.
- Commentaires
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Antigène
- CD40L (Ruplizumab Biosimilar)
- Abstract
- CD40L (Ruplizumab Biosimilar) Produits
- Synonymes
- anticorps CD154, anticorps CD40L, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TNFSF5, anticorps TRAP, anticorps gp39, anticorps hCD40L, anticorps CD40 ligand, anticorps CD40LG
- Classe de substances
- Biosimilar
- Sujet
- CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP
- UniProt
- P29965
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