Recombinant TNF alpha (Adalimumab Biosimilar) anticorps
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- Antigène Tous les produits TNF alpha (Adalimumab Biosimilar)
- TNF alpha (Adalimumab Biosimilar)
- Type d'anticorp
- Recombinant Antibody
- Reactivité
- Humain
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Hôte
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Human
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TNF alpha (Adalimumab Biosimilar) est non-conjugé
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Application
- ELISA, Blocking Reagent (BR), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Specificité
- Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).
- Attributs du produit
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- Purification
- Purified antibody.
- Pureté
- > 98 % as determined by SDS-PAGE
- niveau d'endotoxine
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogène
- This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
- Clone
- D2E7
- Isotype
- IgG1 kappa
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- Indications d'application
- Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.
- Commentaires
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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Scaling eukaryotic cell-free protein synthesis achieved with the versatile and high-yielding tobacco BY-2 cell lysate." dans: Biotechnology and bioengineering, (2023) (PubMed).
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Scaling eukaryotic cell-free protein synthesis achieved with the versatile and high-yielding tobacco BY-2 cell lysate." dans: Biotechnology and bioengineering, (2023) (PubMed).
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- Antigène
- TNF alpha (Adalimumab Biosimilar)
- Abstract
- TNF alpha (Adalimumab Biosimilar) Produits
- Synonymes
- anticorps DIF, anticorps TNF-alpha, anticorps TNFA, anticorps TNFSF2, anticorps tumor necrosis factor, anticorps TNF
- Classe de substances
- Biosimilar
- Sujet
- Tumor necrosis factor alpha
- UniProt
- P01375
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