Recombinant TNF alpha (Adalimumab Biosimilar) anticorps

N° du produit ABIN5668145

Détail du produit anti-TNF alpha (Adalimumab Biosimilar) anticorps

Antigène: TNF alpha (Adalimumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp TNF alpha (Adalimumab Biosimilar) est non-conjugé

Application: ELISA, Blocking Reagent (BR), Immunofluorescence (IF), Immunohistochemistry (IHC)

Specificité: Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).

Attributs du produit:

OriginalSpeciesName: Human

OriginalFormat: IgG1

Purification: Purified antibody.

Pureté: > 98 % as determined by SDS-PAGE

niveau d'endotoxine: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogène: This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).

Clone: D2E7

Isotype: IgG1 kappa

Information d'application

Indications d'application: Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.

Commentaires:

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Références pour anticorps anti-TNF alpha (Adalimumab Biosimilar) (ABIN5668145)

Gupta, Flaskamp, Roentgen, Juergens, Armero-Gimenez, Albrecht, Hemmerich, Arfi, Neuser, Spiegel, Schillberg, Yeliseev, Song, Qiu, Williams, Finnern: "Scaling eukaryotic cell-free protein synthesis achieved with the versatile and high-yielding tobacco BY-2 cell lysate." dans: Biotechnology and bioengineering, (2023) (PubMed).

Détails sur TNF alpha (Adalimumab Biosimilar)

Antigène: TNF alpha (Adalimumab Biosimilar)

Abstract: TNF alpha (Adalimumab Biosimilar) Produits

Synonymes: anticorps DIF, anticorps TNF-alpha, anticorps TNFA, anticorps TNFSF2, anticorps tumor necrosis factor, anticorps TNF

Classe de substances: Biosimilar

Sujet: Tumor necrosis factor alpha

UniProt: P01375