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Recombinant CD32/CD16 anticorps

CD32/CD16 Reactivité: Souris FACS, IP, IF, BR, IHC Hôte: Rat Monoclonal 2-4G2 unconjugated Recombinant Antibody
N° du produit ABIN5668180
  • Antigène Tous les produits CD32/CD16
    CD32/CD16
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Souris
    Hôte
    • 54
    • 1
    • 1
    Rat
    Clonalité
    • 51
    • 1
    • 1
    Monoclonal
    Conjugué
    • 16
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD32/CD16 est non-conjugé
    Application
    • 50
    • 10
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR), Immunohistochemistry (IHC)
    Specificité
    This antibody binds to an epitope on the extracellular domains of the mouse FcγIII and FcγII, thereby inhibiting their ability to bind antibodies via their Fc region. receptors. Also binding the FcγI receptor (CD64) via its Fc domain.
    Attributs du produit

    OriginalSpeciesName: Rat

    OriginalFormat: IgG2b

    Purification
    Purified antibody.
    Immunogène
    Mouse BALB/c Macrophage J774 Cell Line.
    Clone
    2-4G2
    Isotype
    IgG2b kappa
  • Indications d'application
    This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent, to reduce non-specific staining of cells by antibodies binding via their Fc-region. A similar effect can be achieved using the Fc Silent range of antibodies made by Absolute Antibody that prevent these interactions at the level of the Fc receptor binding site, which has been mutated to lack affinity for the Fc receptors.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène
    CD32/CD16
    Autre désignation
    CD16/CD32 (CD32/CD16 Produits)
    Sujet
    Fcγ III/II Receptor, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII IgG Fc rec
    UniProt
    P08508, P08101
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