Recombinant CD33 (Gemtuzumab Biosimilar) anticorps
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- Antigène Tous les produits CD33 (Gemtuzumab Biosimilar)
- CD33 (Gemtuzumab Biosimilar)
- Type d'anticorp
- Recombinant Antibody
- Reactivité
- Humain
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Hôte
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Human
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD33 (Gemtuzumab Biosimilar) est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificité
- Recognises human CD33.
- Attributs du produit
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OriginalSpeciesName: Human
OriginalFormat: IgG4
- Purification
- Purified antibody.
- Pureté
- > 98 % as determined by SDS-PAGE
- niveau d'endotoxine
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogène
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
- Clone
- HP67-6
- Isotype
- IgG4 kappa
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- Indications d'application
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Antigène
- CD33 (Gemtuzumab Biosimilar)
- Abstract
- CD33 (Gemtuzumab Biosimilar) Produits
- Synonymes
- anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps CD33 molecule, anticorps CD33
- Classe de substances
- Biosimilar
- Sujet
- Siglec-3
- UniProt
- P20138
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