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Recombinant CD33 (Gemtuzumab Biosimilar) anticorps

Reactivité: Humain FACS, IF Hôte: Lapin Monoclonal HP67-6 unconjugated Recombinant Antibody
N° du produit ABIN5668211
  • Antigène Tous les produits CD33 (Gemtuzumab Biosimilar)
    CD33 (Gemtuzumab Biosimilar)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 3
    Monoclonal
    Conjugué
    • 3
    Cet anticorp CD33 (Gemtuzumab Biosimilar) est non-conjugé
    Application
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificité
    Recognises human CD33.
    Attributs du produit

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    Purification
    Purified antibody.
    Pureté
    > 98 % as determined by SDS-PAGE
    niveau d'endotoxine
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogène
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    Clone
    HP67-6
    Isotype
    IgG kappa
  • Indications d'application
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) Produits
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps CD33 molecule, anticorps CD33
    Classe de substances
    Biosimilar
    Sujet
    Siglec-3
    UniProt
    P20138
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