Recombinant CD33 (Gemtuzumab Biosimilar) anticorps

N° du produit ABIN5668211

Détail du produit anti-CD33 (Gemtuzumab Biosimilar) anticorps

Antigène: CD33 (Gemtuzumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD33 (Gemtuzumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité: Recognises human CD33.

Attributs du produit:

OriginalSpeciesName: Human

OriginalFormat: IgG4

Purification: Purified antibody.

Pureté: > 98 % as determined by SDS-PAGE

niveau d'endotoxine: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogène: Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.

Clone: HP67-6

Isotype: IgG kappa

Information d'application

Indications d'application: A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD33 (Gemtuzumab Biosimilar)

Antigène: CD33 (Gemtuzumab Biosimilar)

Abstract: CD33 (Gemtuzumab Biosimilar) Produits

Synonymes: anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps CD33 molecule, anticorps CD33

Classe de substances: Biosimilar

Sujet: Siglec-3

UniProt: P20138