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Recombinant ErbB2/Her2 (Trastuzumab Biosimilar) anticorps

Reactivité: Humain FACS, ELISA, IHC Hôte: Lapin Monoclonal 4D5-8 unconjugated Recombinant Antibody
N° du produit ABIN5668227
  • Antigène Tous les produits ErbB2/Her2 (Trastuzumab Biosimilar)
    ErbB2/Her2 (Trastuzumab Biosimilar)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 1
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 4
    Monoclonal
    Conjugué
    • 4
    Cet anticorp ErbB2/Her2 (Trastuzumab Biosimilar) est non-conjugé
    Application
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    Specificité
    Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30 % of invasive breast cancers and 70 % of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
    Attributs du produit

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    Purification
    Purified antibody.
    Pureté
    > 98 % as determined by SDS-PAGE
    niveau d'endotoxine
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogène
    A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
    Clone
    4D5-8
    Isotype
    IgG kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène
    ErbB2/Her2 (Trastuzumab Biosimilar)
    Abstract
    ErbB2/Her2 (Trastuzumab Biosimilar) Produits
    Synonymes
    anticorps CD340, anticorps HER-2, anticorps HER-2/neu, anticorps HER2, anticorps MLN 19, anticorps NEU, anticorps NGL, anticorps TKR1, anticorps erb-b2 receptor tyrosine kinase 2, anticorps ERBB2
    Classe de substances
    Biosimilar
    Sujet
    CD340, Metastatic lymph node gene 19 protein (MLN 19), Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, p185HER2, EGFR
    UniProt
    P04626
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