RICTOR anticorps (AA 1-98)

N° du produit ABIN566975

Détail du produit anti-RICTOR anticorps

Antigène: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Épitope: AA 1-98

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RICTOR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against a partial recombinant RICTOR.

Séquence: MAAIGRGRSL KNLRVRGRND SGEENVPLDL TREPSDNLRE ILQNVARLQG VSNMRKLGHL NNFTKLLCDI GHSEEKLGFH YEDIIICLRL ALLNEAKE

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RICTOR (NP_689969, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1F3

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RICTOR (ABIN566975)

Wu, Schneider, Platen, Mitra, Blazek, Zengerle, Schüle, Meier: "In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 29, pp. E4143-50, (2016) (PubMed).

Pópulo, Tavares, Faustino, Nunes, Lopes, Soares: "GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells." dans: PeerJ, Vol. 1, pp. e104, (2013) (PubMed).

Faustino, Couto, Pópulo, Rocha, Pardal, Cameselle-Teijeiro, Lopes, Sobrinho-Simões, Soares: "mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma." dans: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 7, pp. E1139-49, (2012) (PubMed).

Naïmi, Gautier, Chaussade, Valverde, Accili, Van Obberghen: "Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes." dans: Endocrinology, Vol. 148, Issue 5, pp. 2424-34, (2007) (PubMed).

Détails sur RICTOR

Antigène: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Autre désignation: RICTOR (RICTOR Produits)

Sujet: Full Gene Name: rapamycin-insensitive companion of mTOR
Synonyms: DKFZp686B11164,KIAA1999,MGC39830,mAVO3

ID gène: 253260

NCBI Accession: NM_152756

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events