Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Conseil sur la manipulation
Aliquot to avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Wu, Schneider, Platen, Mitra, Blazek, Zengerle, Schüle, Meier: "In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 29, pp. E4143-50, (2016) (PubMed).
Pópulo, Tavares, Faustino, Nunes, Lopes, Soares: "GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells." dans: PeerJ, Vol. 1, pp. e104, (2013) (PubMed).
Faustino, Couto, Pópulo, Rocha, Pardal, Cameselle-Teijeiro, Lopes, Sobrinho-Simões, Soares: "mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma." dans: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 7, pp. E1139-49, (2012) (PubMed).
Naïmi, Gautier, Chaussade, Valverde, Accili, Van Obberghen: "Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes." dans: Endocrinology, Vol. 148, Issue 5, pp. 2424-34, (2007) (PubMed).
Antigène
RICTOR
(RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))