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ERO1L anticorps (AA 321-420)

ERO1L Reactivité: Humain WB, ELISA, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5675519
  • Antigène Voir toutes ERO1L Anticorps
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420
    Reactivité
    • 43
    • 4
    • 4
    Humain
    Hôte
    • 37
    • 5
    • 1
    Lapin
    Clonalité
    • 40
    • 2
    Polyclonal
    Conjugué
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERO1L est non-conjugé
    Application
    • 43
    • 21
    • 19
    • 15
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ERO1L
    Isotype
    IgG
    Top Product
    Discover our top product ERO1L Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Autre désignation
    ERO1L (ERO1L Produits)
    Synonymes
    anticorps ERO1-L, anticorps ero1-alpha, anticorps ero1lb, anticorps ERO1L, anticorps ero1l, anticorps ERO1-alpha, anticorps ERO1A, anticorps zgc:63959, anticorps endoplasmic reticulum oxidoreductase alpha L homeolog, anticorps endoplasmic reticulum oxidoreductase 1 alpha, anticorps endoplasmic reticulum oxidoreductase alpha, anticorps ERO1-like (S. cerevisiae), anticorps ero1a.L, anticorps ERO1A, anticorps ero1a, anticorps Ero1l, anticorps Ero1a
    Sujet

    Synonyms: ERO1-like protein alpha, ERO1A, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha, ERO1L

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

    ID gène
    30001
    UniProt
    Q96HE7
    Pathways
    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
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