ERO1LB anticorps (AA 1-100) (Biotin)

N° du produit ABIN5675592

Détail du produit anti-ERO1LB anticorps (Biotin)

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Épitope: AA 1-100

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERO1LB est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ERO1LB

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ERO1LB

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Autre désignation: ERO1LB (ERO1LB Produits)

Synonymes: anticorps RGD1563548, anticorps 1300013B24Rik, anticorps 1700065B09Rik, anticorps AI447560, anticorps ero1-beta, anticorps endoplasmic reticulum oxidoreductase 1 beta, anticorps ERO1-like beta (S. cerevisiae), anticorps Ero1b, anticorps ERO1B, anticorps Ero1lb

Sujet:

Synonyms: Endoplasmic oxidoreductin-1-like protein B, ERO1-L-beta, ERO1B, ERO1-like protein beta, Oxidoreductin-1-L-beta

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

ID gène: 56605

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interactome