EXD2 anticorps (AA 351-621) (AbBy Fluor® 647)
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- Antigène Tous les produits EXD2
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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Épitope
- AA 351-621
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EXD2 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificité
- WB shows isoform 2
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human EXD2
- Isotype
- IgG
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
- Autre désignation
- EXD2 (EXD2 Produits)
- Synonymes
- anticorps C14orf114, anticorps EXDL2, anticorps 4930539P14Rik, anticorps C85658, anticorps Exdl2, anticorps RGD1311087, anticorps exd2-b, anticorps exdl2, anticorps fi72h12, anticorps wu:fi72h12, anticorps zgc:175195, anticorps exd2, anticorps exd2-a, anticorps exonuclease 3'-5' domain containing 2, anticorps exonuclease 3'-5' domain containing 2 b, anticorps EXD2, anticorps Exd2, anticorps exd2.S, anticorps exd2, anticorps exd2.L
- Sujet
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Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- ID gène
- 55218
- UniProt
- Q9NVH0
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