EXD2 anticorps (AA 351-621) (Biotin)

N° du produit ABIN5675763

Détail du produit anti-EXD2 anticorps (Biotin)

Antigène: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Épitope: AA 351-621

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXD2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: WB shows isoform 2

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EXD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EXD2

Antigène: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Autre désignation: EXD2 (EXD2 Produits)

Synonymes: anticorps C14orf114, anticorps EXDL2, anticorps 4930539P14Rik, anticorps C85658, anticorps Exdl2, anticorps RGD1311087, anticorps exd2-b, anticorps exdl2, anticorps fi72h12, anticorps wu:fi72h12, anticorps zgc:175195, anticorps exd2, anticorps exd2-a, anticorps exonuclease 3'-5' domain containing 2, anticorps exonuclease 3'-5' domain containing 2 b, anticorps EXD2, anticorps Exd2, anticorps exd2.S, anticorps exd2, anticorps exd2.L

Sujet:

Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

ID gène: 55218

UniProt: Q9NVH0