NQO2 anticorps

N° du produit ABIN567621

Détail du produit anti-NQO2 anticorps

Antigène: NQO2

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NQO2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: The antibody recognizes human and mouse NQO2. Other species not tested.

Purification: Protein-G affinity chromatography

Clone: AT1E3

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur NQO2

Antigène: NQO2

Autre désignation: NQO2 (NQO2 Produits)

Synonymes: anticorps DHQV, anticorps DIA6, anticorps NMOR2, anticorps QR2, anticorps NMO2, anticorps Nmor2, anticorps Ox2, anticorps N-ribosyldihydronicotinamide:quinone reductase 2, anticorps N-ribosyldihydronicotinamide quinone reductase 2, anticorps NQO2, anticorps Nqo2

Sujet: Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates.NQO2 is inhibited by flavones such as quercetin. Also benzo(a)pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates.The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.Synonyms: NMOR2, NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Ribosyldihydronicotinamide dehydrogenase [quinone]

ID gène: 4835