CD3D anticorps (AA 22-105)

N° du produit ABIN5684129

Détail du produit anti-CD3D anticorps

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Épitope: AA 22-105

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD3D (AA: extra 22-105) expressed in E. coli.

Clone: 8D11D5

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur CD3D

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Autre désignation: CD3D (CD3D Produits)

Synonymes: anticorps CD3-DELTA, anticorps T3D, anticorps CD3, anticorps T3d, anticorps CD3d molecule, anticorps CD3 antigen, delta polypeptide, anticorps CD3D, anticorps Cd3d

Sujet:

Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Aliases: T3D, IMD19, CD3-DELTA

Poids moléculaire: 18.9 kDa

ID gène: 915

HGNC: 10666

Pathways: TCR Signaling, CXCR4-mediated Signaling Events