LAIR1 anticorps (AA 22-165)

N° du produit ABIN5684133

Détail du produit anti-LAIR1 anticorps

Antigène: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Épitope: AA 22-165

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAIR1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CD305 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD305 (AA: 22-165) expressed in E. Coli.

Clone: 1G8B6

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur LAIR1

Antigène: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Autre désignation: CD305 (LAIR1 Produits)

Synonymes: anticorps 5133400O11Rik, anticorps BB115266, anticorps D7Bwg0421e, anticorps Lair-1, anticorps mLair-1, anticorps CD305, anticorps LAIR-1, anticorps leukocyte-associated Ig-like receptor 1, anticorps leukocyte associated immunoglobulin like receptor 1, anticorps leukocyte-associated immunoglobulin-like receptor 1, anticorps Lair1, anticorps LAIR1

Sujet:

Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

Aliases: LAIR1, LAIR-1

Poids moléculaire: 31.4kDa

ID gène: 3903

HGNC: 967

UniProt: Q6GTX8