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Connexin anticorps (C-Term)

Reactivité: Mouton, Xenopus laevis, Poisson zèbre (Danio rerio), Poulet, Chien, Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5688865
  • Antigène Tous les produits Connexin
    Connexin
    Épitope
    C-Term
    Reactivité
    Mouton, Xenopus laevis, Poisson zèbre (Danio rerio), Poulet, Chien, Humain, Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Western Blotting (WB)
    Purification
    Affinity Purified
    Immunogène
    Peptide corresponding to amino acid residues from the C-terminal region of rat connexin43.
  • Indications d'application
    The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will also work with chicken, dog, finch, human, mouse, non-human primate, sheep, Xenopus and zebra fish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Connexin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Antigène
    Connexin
    Abstract
    Connexin Produits
    Synonymes
    anticorps connexin, anticorps LOC100128922
    Sujet
    Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).
    Poids moléculaire
    43 kDa
    ID gène
    24392
    UniProt
    P08050
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