Connexin anticorps (C-Term)

N° du produit ABIN5688865

Détail du produit anti-Connexin anticorps

Antigène: Connexin

Épitope: C-Term

Reactivité: Mouton, Xenopus laevis, Poisson zèbre (Danio rerio), Poulet, Chien, Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Purification: Affinity Purified

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of rat connexin43.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will also work with chicken, dog, finch, human, mouse, non-human primate, sheep, Xenopus and zebra fish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: Connexin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur Connexin

Antigène: Connexin

Abstract: Connexin Produits

Synonymes: anticorps connexin, anticorps LOC100128922

Sujet: Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).

Poids moléculaire: 43 kDa

ID gène: 24392

UniProt: P08050