Synaptophysin 2 anticorps (AA 257-261)

N° du produit ABIN5689618

Détail du produit anti-Synaptophysin 2 anticorps

Antigène: Synaptophysin 2

Épitope: AA 257-261

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptophysin 2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of total synaptophysin 2 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: synaptophysin 2 antibody was raised against a peptide sequence around aa.257~261 (G-P-T-S-F) derived from Rat synaptophysin 2.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur Synaptophysin 2

Antigène: Synaptophysin 2

Abstract: Synaptophysin 2 Produits

Synonymes: anticorps synaptoporin, anticorps Synpr

Sujet: Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

Poids moléculaire: 37 kDa

ID gène: 66030

NCBI Accession: NP_076464

UniProt: P22831