DIS3 anticorps (AA 90-140)
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- Antigène Voir toutes DIS3 Anticorps
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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Épitope
- AA 90-140
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DIS3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- Multiple isoforms of DIS3 are known to exist.
- Purification
- DIS3 Antibody is affinity chromatography purified via peptide column.
- Immunogène
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DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3.
The immunogen is located within amino acids 90 - 140 of DIS3. - Isotype
- IgG
- Top Product
- Discover our top product DIS3 Anticorps primaire
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- Indications d'application
- DIS3 antibody can be used for detection of DIS3 by Western blot at 1 - 2 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- DIS3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- DIS3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
- Autre désignation
- DIS3 (DIS3 Produits)
- Synonymes
- anticorps EXOSC11, anticorps KIAA1008, anticorps RP11-342J4.3, anticorps RRP44, anticorps bA555G22.1, anticorps dis3p, anticorps DIS3, anticorps 2810028N01Rik, anticorps RGD1304646, anticorps wu:fb08g12, anticorps dis3, anticorps DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease, anticorps DIS3 exosome endoribonuclease and 3'-5' exoribonuclease, anticorps DIS3, anticorps Dis3, anticorps dis3, anticorps dis3.L
- Sujet
- DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.
- Poids moléculaire
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Predicted: 105 kDa
Observed: 103 kDa - ID gène
- 22894
- NCBI Accession
- NP_055768
- UniProt
- Q9Y2L1
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