LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist, this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.
Purification
LAMTOR3 antibody is affinity chromatography purified via peptide column.
Immunogène
LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3.
The immunogen is located within amino acids 40 - 90 of LAMTOR3.
MAPKSP1
Reactivité: Souris
IF (p), IF (cc)
Hôte: Lapin
Polyclonal
AbBy Fluor® 555
Indications d'application
LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
LAMTOR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
MAPKSP1
(Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).