Neuroligin 2 anticorps (AA 630-680)

N° du produit ABIN5690079

Détail du produit anti-Neuroligin 2 anticorps

Antigène: Neuroligin 2 (NLGN2)

Épitope: AA 630-680

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuroligin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.

Purification: NLGN2 antibody is affinity chromatography purified via peptide column.

Immunogène: NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2.

The immunogen is located within amino acids 630 - 680 of NLGN2.

Isotype: IgG

Information d'application

Indications d'application: NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NLGN2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Neuroligin 2

Antigène: Neuroligin 2 (NLGN2)

Autre désignation: NLGN2 (NLGN2 Produits)

Sujet: Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).

Poids moléculaire: Predicted: 92, 99 kDa

Observed: 80, 97 kDa

ID gène: 57555

NCBI Accession: NP_065846

UniProt: Q8NFZ4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane