WSB1 anticorps (AA 70-120)
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- Antigène Voir toutes WSB1 Anticorps
- WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))
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Épitope
- AA 70-120
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WSB1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- WSB1 antibody is human specific.
- Purification
- WSB1 antibody is affinity chromatography purified via peptide column.
- Immunogène
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WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1.
The immunogen is located within amino acids 70 - 120 of WSB1. - Isotype
- IgG
- Top Product
- Discover our top product WSB1 Anticorps primaire
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- Indications d'application
- WSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- WSB1 antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- WSB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))
- Autre désignation
- WSB1 (WSB1 Produits)
- Synonymes
- anticorps SWIP1, anticorps WSB-1, anticorps 1110056B13Rik, anticorps 2700038M07Rik, anticorps wu:fb92g11, anticorps zgc:63905, anticorps WD repeat and SOCS box containing 1, anticorps WD repeat and SOCS box-containing 1, anticorps WSB1, anticorps Wsb1, anticorps wsb1
- Sujet
- The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).
- Poids moléculaire
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Predicted: 46 kDa
Observed: 46 kDa - ID gène
- 26118
- NCBI Accession
- NP_056441
- UniProt
- Q9Y6I7
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