Bestrophin 1 anticorps (DyLight 488)

N° du produit ABIN7354625

Détail du produit anti-Bestrophin 1 anticorps (DyLight 488)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est conjugé à/à la DyLight 488

Application: Flow Cytometry (FACS)

Séquence: RFIYRLALTE EQQLMFEKLT LYCD

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG Polyclonal Anti-Human Bestrophin Antibody DyLight® 488 Conjugated, Flow Validated.

Immunogène: A synthetic peptide corresponding to a sequence of human Bestrophin (RFIYRLALTEEQQLMFEKLTLYCD).

Information d'application

Indications d'application:

Application Details: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: At 2-8°C for one year. Protect from light. Do not freeze.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: BEST1 (BEST1 Produits)

Synonymes: anticorps CG6264, anticorps Dbest, anticorps Dmel\\CG6264, anticorps anon-WO0118547.380, anticorps best, anticorps dBest1, anticorps dbest1, anticorps dmBest1, anticorps BEST1, anticorps VMD2, anticorps best-1, anticorps ARB, anticorps BEST, anticorps BMD, anticorps RP50, anticorps TU15B, anticorps Bmd, anticorps Vmd2, anticorps mBest1, anticorps Bestrophin 1, anticorps bestrophin 1, anticorps Best1, anticorps BEST1, anticorps best1, anticorps Bm1_25500

Sujet:

Synonyms: Bestrophin-1, TU15B, Vitelliform macular dystrophy protein 2, BEST1, VMD2

Tissue Specificity: Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.

Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

UniProt: O76090