Prothrombin anticorps (AA 67-124)

N° du produit ABIN5693261

Détail du produit anti-Prothrombin anticorps

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Épitope: AA 67-124

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prothrombin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Prothrombin detection. Tested with WB, IHC-P, Direct ELISA in Human.

Immunogène: E. coli-derived human Prothrombin recombinant protein (Position: Y67-R124).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Prothrombin (ABIN5693261)

Shen, Fang, Lv, Pei, Wang, Jiang, Ding: "Heparin impairs angiogenesis through inhibition of microRNA-10b." dans: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2 (F2 Produits)

Synonymes: anticorps PT, anticorps RPRGL2, anticorps THPH1, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps zgc:66319, anticorps wu:fb57c10, anticorps wu:fd42e09, anticorps wu:fd59d01, anticorps prothrombin, anticorps F2, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, anticorps coagulation factor II (thrombin), anticorps F2, anticorps f2

Sujet:

Synonyms: Prothrombin, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2

Tissue Specificity: Expressed by the liver and secreted in plasma.

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

UniProt: P00734

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling