PDE4D anticorps (AA 466-709)

N° du produit ABIN5693278

Détail du produit anti-PDE4D anticorps

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Épitope: AA 466-709

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for PDE4D detection. Tested with WB, IHC-P, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human PDE4D recombinant protein (Position: H466-Q709).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x10⁶ cells
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur PDE4D

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Autre désignation: PDE4D (PDE4D Produits)

Synonymes: anticorps ACRDYS2, anticorps DPDE3, anticorps HSPDE4D, anticorps PDE43, anticorps PDE4DN2, anticorps STRK1, anticorps CMYA2, anticorps MMGL, anticorps 9630011N22Rik, anticorps Dpde3, anticorps 4732458A06Rik, anticorps 9430063L05Rik, anticorps C87016, anticorps D130016K21Rik, anticorps D3Bwg1078e, anticorps Usmg4, anticorps mKIAA0454, anticorps si:dkey-190g11.2, anticorps phosphodiesterase 4D, anticorps phosphodiesterase 4D interacting protein, anticorps phosphodiesterase 4D, cAMP specific, anticorps phosphodiesterase 4D, cAMP-specific, anticorps phosphodiesterase 4D interacting protein (myomegalin), anticorps PDE4D, anticorps PDE4DIP, anticorps pde4d, anticorps Pde4dip, anticorps Pde4d

Sujet:

Synonyms: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, DPDE3, PDE43, PDE4D, DPDE3

Tissue Specificity: Expressed in colonic epithelial cells (at protein level). Widespread, most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Background: cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene. This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling