SCRIB anticorps (AA 172-409)

N° du produit ABIN5693286

Détail du produit anti-SCRIB anticorps

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Épitope: AA 172-409

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCRIB est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for SCRIBBLE detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x10⁶ cells
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur SCRIB

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Autre désignation: SCRIB (SCRIB Produits)

Synonymes: anticorps 0424/05, anticorps CG31082, anticorps CG42614, anticorps CG43398, anticorps CG5462, anticorps CG5467, anticorps CT17324, anticorps Dmel\\CG43398, anticorps Dmel_CG31082, anticorps Dmel_CG42614, anticorps Dmel_CG5462, anticorps Dmel_CG5467, anticorps MENE (3R)-F, anticorps SCR, anticorps Scb, anticorps Scrb, anticorps Scrib, anticorps ird, anticorps ird15, anticorps l(3)673, anticorps l(3)S042405, anticorps l(3)c00119, anticorps l(3)j7B3, anticorps scrb, anticorps smi97B, anticorps vart, anticorps AI118201, anticorps CRIB, anticorps Crc, anticorps SCRIB1, anticorps Scrb1, anticorps mKIAA0147, anticorps vartul, anticorps scrb1, anticorps scribble, anticorps scribble1, anticorps si:ch211-12p8.1, anticorps si:zc12p8.1, anticorps CRIB1, anticorps SCRB1, anticorps Vartul, anticorps scribbled, anticorps scribbled planar cell polarity, anticorps scribbled planar cell polarity protein, anticorps scrib, anticorps Scrib, anticorps SCRIB

Sujet:

Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).

Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization