IMPA1 anticorps
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- Antigène Voir toutes IMPA1 Anticorps
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IMPA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Immunogène
- inositol(myo)-1(or 4)-monophosphatase 1
- Isotype
- IgG
- Top Product
- Discover our top product IMPA1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04300(IMPA1 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
- Autre désignation
- IMPA1 (IMPA1 Produits)
- Synonymes
- anticorps zgc:100926, anticorps 2610002K09Rik, anticorps 2900059K10Rik, anticorps AI325909, anticorps IMP, anticorps IMPA, anticorps impa, anticorps inositol monophosphatase 1, anticorps inositol(myo)-1(or 4)-monophosphatase 1, anticorps inositol (myo)-1(or 4)-monophosphatase 1, anticorps inositol monophosphatase, anticorps inositol(myo)-1(or 4)-monophosphatase 1 S homeolog, anticorps impa1, anticorps Impa1, anticorps IMPA1, anticorps impa1.S
- Sujet
- Synonyms:IMPA Background:This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1, 4, 5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1, 3-diphosphate, myo-inositol-1, 4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti- manic and anti- depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
- Poids moléculaire
- 30 kDa
- ID gène
- 3612
- UniProt
- P29218
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