GPSM1 anticorps
-
- Antigène Voir toutes GPSM1 Anticorps
- GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GPSM1 est non-conjugé
-
Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogène
- G-protein signaling modulator 1 (AGS3-like, C. elegans)
- Isotype
- IgG
- Top Product
- Discover our top product GPSM1 Anticorps primaire
-
-
- Indications d'application
- WB :1:200-1:2000,IF:1:10-1:100,IHC:1:20-1:200
- Commentaires
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(GPSM1 antibody) at dilution of 1:600
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
-
- Antigène
- GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))
- Autre désignation
- AGS3 (GPSM1 Produits)
- Synonymes
- anticorps 1810037C22Rik, anticorps AW107933, anticorps Ags3, anticorps AGS3, anticorps ags3, anticorps gpsm1, anticorps G-protein signalling modulator 1 (AGS3-like, C. elegans), anticorps G-protein signaling modulator 1, anticorps G protein signaling modulator 1, anticorps G-protein signaling modulator 1 L homeolog, anticorps Gpsm1, anticorps GPSM1, anticorps gpsm1.L
- Sujet
- Synonyms:AGS3, DKFZp727I051, GPSM1 Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).
- Poids moléculaire
- 72kDa
- UniProt
- Q86YR5
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
-