NUMBL anticorps
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- Antigène Voir toutes NUMBL Anticorps
- NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NUMBL est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogène
- numb homolog (Drosophila)-like
- Isotype
- IgG2a
- Top Product
- Discover our top product NUMBL Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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L02 cells were subjected to SDS PAGE followed by western blot with FNab05918( NUMBLIKE Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
- Autre désignation
- NUMBL (NUMBL Produits)
- Synonymes
- anticorps nbl, anticorps numb, anticorps cag3a, anticorps ctg3a, anticorps numbr, anticorps numb-r, anticorps tnrc23, anticorps numblike, anticorps CAG3A, anticorps CTG3a, anticorps NBL, anticorps NUMB-R, anticorps NUMBLIKE, anticorps NUMBR, anticorps TNRC23, anticorps NUMB like, endocytic adaptor protein, anticorps numb homolog-like L homeolog, anticorps NUMB-like, endocytic adaptor protein, anticorps numb-like, anticorps NUMBL, anticorps numbl.L, anticorps Numbl
- Sujet
- Synonyms: Background:Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells(RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone(SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
- Poids moléculaire
- 65-70 kDa
- ID gène
- 9253
- UniProt
- Q9Y6R0
- Pathways
- Cell-Cell Junction Organization
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