PAN2 anticorps
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- Antigène Voir toutes PAN2 Anticorps
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAN2 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Immunogène
- PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
- Isotype
- IgG
- Top Product
- Discover our top product PAN2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab06131(PAN2 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
- Autre désignation
- PAN2 (PAN2 Produits)
- Synonymes
- anticorps USP52, anticorps 1200014O24Rik, anticorps AI047843, anticorps AW742773, anticorps Usp52, anticorps mKIAA0710, anticorps PAN2, anticorps pan2, anticorps PAN2 poly(A) specific ribonuclease subunit, anticorps PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae), anticorps PAN2 poly(A) specific ribonuclease subunit S homeolog, anticorps PAN2, anticorps Pan2, anticorps pan2.S
- Sujet
- Synonyms:KIAA0710, USP52 Background:Catalytic subunit of the poly(A)-nuclease(PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein(PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
- ID gène
- 9924
- UniProt
- Q504Q3
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