NKX2-1 anticorps
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- Antigène Voir toutes NKX2-1 Anticorps
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NKX2-1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Purified
- Pureté
- Protein A affinity chromatography
- Immunogène
- Recombinant protein was used as the immunogen for the recombinant NKX2.1 antibody.
- Clone
- NX2-1-1855R
- Isotype
- IgG kappa
- Top Product
- Discover our top product NKX2-1 Anticorps primaire
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- Indications d'application
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Optimal dilution of the recombinant NKX2.1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) - Restrictions
- For Research Use only
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- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the recombinant NKX2.1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Antigène
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- Autre désignation
- NKX2.1 / TTF1 (NKX2-1 Produits)
- Synonymes
- anticorps BCH, anticorps BHC, anticorps NK-2, anticorps NKX2.1, anticorps NKX2A, anticorps TEBP, anticorps TITF1, anticorps TTF-1, anticorps TTF1, anticorps titf1-A, anticorps Xnkx-2.1, anticorps NKX2-1, anticorps LOC100227803, anticorps AV026640, anticorps Nkx2.1, anticorps T/EBP, anticorps Titf1, anticorps Ttf-1, anticorps nk2.1a, anticorps nkx2.1, anticorps nkx2.4a, anticorps titf1, anticorps titf1a, anticorps NK2 homeobox 1, anticorps NK2 homeobox 1 L homeolog, anticorps NK2 homeobox 4b, anticorps NKX2-1, anticorps nkx2-1.L, anticorps Nkx2-1, anticorps nkx2.4b
- Sujet
- NKX2.1/TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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