ABCE1 anticorps

N° du produit ABIN5708515

Cet anticorps anti-ABCE1 Polyclonal Lapin (ABIN5708515) détecte spécifiquement ABCE1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ABCE1 anticorps (ABIN5708515)

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit anti-ABCE1 anticorps

Purification: Antigen affinity purified

Immunogène: Amino acids K419-D599 from the human protein were used as the immunogen for the ABCE1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the ABCE1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ABCE1

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Autre désignation: ABCE1 / ATP binding cassette E1

Sujet: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

UniProt: P61221