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CD42a anticorps (APC)

GP9 Reactivité: Humain, Chien FACS Hôte: Souris Monoclonal GR-P APC
N° du produit ABIN5710576
  • Antigène Voir toutes CD42a (GP9) Anticorps
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Reactivité
    • 56
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Chien
    Hôte
    • 40
    • 19
    Souris
    Clonalité
    • 42
    • 17
    Monoclonal
    Conjugué
    • 24
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD42a est conjugé à/à la APC
    Application
    • 26
    • 21
    • 19
    • 13
    • 13
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
    Réactivité croisée (Details)
    Human, Canine (Dog)
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human acute lymphoblastic leukemia cells
    Clone
    GR-P
    Isotype
    IgG1
    Top Product
    Discover our top product GP9 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Autre désignation
    CD42a (GP9 Produits)
    Synonymes
    anticorps cd42a, anticorps gpix, anticorps GP9, anticorps GPIX, anticorps Cd42, anticorps CD42a, anticorps glycoprotein IX platelet, anticorps glycoprotein IX platelet L homeolog, anticorps glycoprotein IX (platelet), anticorps glycoprotein 9 (platelet), anticorps GP9, anticorps gp9.L, anticorps Gp9
    Sujet
    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9
    ID gène
    2815
    UniProt
    P14770
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