Caspase 5 p20 anticorps (Cleaved-Asp121)

N° du produit ABIN5955946

Détail du produit anti-Caspase 5 p20 anticorps

Antigène: Caspase 5 p20

Épitope: Cleaved-Asp121

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 5 p20 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human Caspase-5 p20

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Caspase 5 p20

Antigène: Caspase 5 p20

Autre désignation: Caspase-5 p20 (Caspase 5 p20 Produits)

Sujet: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Poids moléculaire: 48kDa

ID gène: 838

UniProt: P51878