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GSK3 alpha/beta anticorps (Tyr216, Tyr279)
GSK3a/b
Reactivité: Humain, Rat, Souris
WB, ELISA, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5956808
Détail du produit anti-GSK3 alpha/beta anticorps
(cache)
Antigène
Tous les produits GSK3 alpha/beta (GSK3a/b)
GSK3 alpha/beta (GSK3a/b)
(Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
Épitope
Tous les épitopes à travers GSK3 alpha/beta Anticorps.
Tyr216, Tyr279
Reactivité
Toutes les réactivités sur GSK3 alpha/beta Anticorps
Humain, Rat, Souris
Hôte
Toutes les hôtes sur GSK3 alpha/beta Anticorps
Lapin
Clonalité
Toutes les clonalités sur GSK3 alpha/beta Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers GSK3 alpha/beta Anticorps
Cet anticorp GSK3 alpha/beta est non-conjugé
Application
Tous les applications à travers GSK3 alpha/beta Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
GSK3A,Glycogen synthase kinase-3 alpha,GSK-3 alpha,Serine/threonine-protein kinase GSK3A,GSK3B,Glycogen synthase kinase-3 beta,GSK-3 beta,Serine/threonine-protein kinase GSK3B
Purification
Affinity purification
Immunogène
Synthesized peptide derived from human GSK3alpha/beta around the non-phosphorylation site of Tyr279/216.
Isotype
IgG
Alternatives
(show)
Information d'application
(cache)
Indications d'application
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur GSK3 alpha/beta
(cache)
Antigène
GSK3 alpha/beta (GSK3a/b)
(Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
Autre désignation
GSK3 alpha/beta (GSK3a/b Produits )
Sujet
Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3βGSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.
Poids moléculaire
51kDa
ID gène
2931
Vus récemment
(cache)