CMA1 anticorps
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- Antigène Voir toutes CMA1 Anticorps
- CMA1 (Chymase 1, Mast Cell (CMA1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CMA1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Alpha-chymase,Chymase 1,Chymase 1 mast cell,chymase 1 preproprotein transcript E,chymase 1 preproprotein transcript I,Chymase,Chymase,heart,Chymase,mast cell,CMA1,CMA1,CYH,CYM,EC 3.4.21.39,Mast cell chymase 1,Mast cell protease 3,Mast cell protease 5,Mast cell protease I,Mast cell protease III,Mcp-5,MCP3P,Mcpt5,MCT1,MGC119890,MGC119891,MMCP-5
- Purification
- Affinity purification
- Immunogène
- Synthesized peptide derived from the Internal region of human Chymase.
- Isotype
- IgG
- Top Product
- Discover our top product CMA1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA 1:20000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CMA1 (Chymase 1, Mast Cell (CMA1))
- Autre désignation
- Chymase (CMA1 Produits)
- Synonymes
- anticorps CYH, anticorps MCT1, anticorps chymase, anticorps MMCP-5, anticorps Mcp-5, anticorps Mcp5, anticorps Mcpt5, anticorps MCP3P, anticorps CMA1, anticorps Chymase, anticorps chymase 1, anticorps chymase 1, mast cell, anticorps chymase-like, anticorps CMA1, anticorps Cma1, anticorps LOC100008644
- Sujet
- This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.CMA1 (Chymase 1) is a Protein Coding gene. Diseases associated with CMA1 include Urticaria Pigmentosa and Urticaria. Among its related pathways are Degradation of the extracellular matrix and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is GZMB.
- Poids moléculaire
- 27kDa
- ID gène
- 1215
- UniProt
- P23946
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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