AGR2 anticorps (AA 21-175)

N° du produit ABIN6136646

Détail du produit anti-AGR2 anticorps

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Épitope: AA 21-175

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2 (AGR2 Produits)

Synonymes: anticorps AG2, anticorps GOB-4, anticorps HAG-2, anticorps PDIA17, anticorps XAG-2, anticorps Agr2h, anticorps Gob-4, anticorps mAG-2, anticorps wu:fj29g05, anticorps zgc:112187, anticorps agr2, anticorps hag3, anticorps hag-3, anticorps bcmp11, anticorps MGC89004, anticorps XAgr2, anticorps agr2-A, anticorps anterior gradient 2, protein disulphide isomerase family member, anticorps anterior gradient 2, anticorps anterior gradient 3, protein disulphide isomerase family member, anticorps anterior gradient 2, protein disulphide isomerase family member S homeolog, anticorps AGR2, anticorps Agr2, anticorps agr2, anticorps agr3, anticorps agr2.S

Sujet: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.,AGR2,AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,AGR2

Poids moléculaire: 19 kDa

ID gène: 10551

UniProt: O95994