ALKBH4 anticorps (AA 1-302)

N° du produit ABIN6136802

Détail du produit anti-ALKBH4 anticorps

Antigène: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Épitope: AA 1-302

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MAAAAAETPE VLRECGCKGI RTCLICERQR GSDPPWELPP AKTYRFIYCS DTGWAVGTEE SDFEGWAFPF PGVMLIEDFV TREEEAELVR LMDRDPWKLS QSGRRKQDYG PKVNFRKQKL KTEGFCGLPS FSREVVRRMG LYPGLEGFRP VEQCNLDYCP ERGSAIDPHL DDAWLWGERL VSLNLLSPTV LSMCREAPGS LLLCSAPSAA PEALVDSVIA PSRSVLCQEV EVAIPLPARS LLVLTGAARH QWKHAIHRRH IEARRVCVTF RELSAEFGPG GRQQELGQEL LRIALSFQGR PV

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human ALKBH4 (NP_060091.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH4

Antigène: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Autre désignation: ALKBH4 (ALKBH4 Produits)

Synonymes: anticorps ABH4, anticorps 2010004B12Rik, anticorps Abj4, anticorps alkB homolog 4, lysine demethylase, anticorps ALKBH4, anticorps Alkbh4

Sujet: Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1, thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6-methyladenosine DNA, thereby regulating Polycomb silencing (By similarity.,ALKBH4,ABH4,Epigenetics & Nuclear Signaling,DNA Damage & Repair,ALKBH4

Poids moléculaire: 4 kDa/33 kDa

ID gène: 54784

UniProt: Q9NXW9