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ALKBH5 anticorps (AA 245-394)

ALKBH5 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6136806
  • Antigène Voir toutes ALKBH5 Anticorps
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    AA 245-394
    Reactivité
    • 25
    • 24
    • 17
    Humain
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 40
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALKBH5 est non-conjugé
    Application
    • 18
    • 18
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SLPVRRGSVT VLSGYAADEI THCIRPQDIK ERRAVIILRK TRLDAPRLET KSLSSSVLPP SYASDRLSGN NRDPALKPKR SHRKADPDAA HRPRILEMDK EENRRSVLLP THRRRGSFSS ENYWRKSYES SEDCSEAAGS PARKVKMRRH
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3).
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH5 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Autre désignation
    ALKBH5 (ALKBH5 Produits)
    Synonymes
    anticorps RGD1309496, anticorps ABH5, anticorps OFOXD, anticorps OFOXD1, anticorps AW050020, anticorps AW215868, anticorps Abh5, anticorps E130207K11, anticorps Ofoxd, anticorps alkB homolog 5, RNA demethylase, anticorps alkB homolog 5, RNA demethylase L homeolog, anticorps Alkbh5, anticorps alkbh5.L, anticorps ALKBH5
    Sujet
    Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.,ALKBH5,ABH5,OFOXD,OFOXD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,ALKBH5
    Poids moléculaire
    43 kDa/44 kDa/52 kDa
    ID gène
    54890
    UniProt
    Q6P6C2
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