ALKBH5 anticorps (AA 245-394)

N° du produit ABIN6136806

Détail du produit anti-ALKBH5 anticorps

Antigène: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Épitope: AA 245-394

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH5 est non-conjugé

Application: Western Blotting (WB)

Séquence: SLPVRRGSVT VLSGYAADEI THCIRPQDIK ERRAVIILRK TRLDAPRLET KSLSSSVLPP SYASDRLSGN NRDPALKPKR SHRKADPDAA HRPRILEMDK EENRRSVLLP THRRRGSFSS ENYWRKSYES SEDCSEAAGS PARKVKMRRH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH5

Antigène: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Autre désignation: ALKBH5 (ALKBH5 Produits)

Synonymes: anticorps RGD1309496, anticorps ABH5, anticorps OFOXD, anticorps OFOXD1, anticorps AW050020, anticorps AW215868, anticorps Abh5, anticorps E130207K11, anticorps Ofoxd, anticorps alkB homolog 5, RNA demethylase, anticorps alkB homolog 5, RNA demethylase L homeolog, anticorps Alkbh5, anticorps alkbh5.L, anticorps ALKBH5

Sujet: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.,ALKBH5,ABH5,OFOXD,OFOXD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,ALKBH5

Poids moléculaire: 43 kDa/44 kDa/52 kDa

ID gène: 54890

UniProt: Q6P6C2