APLP1 anticorps (AA 39-300)

N° du produit ABIN6136993

Détail du produit anti-APLP1 anticorps

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Épitope: AA 39-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 39-300 of human APLP1 (NP_005157.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APLP1

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Autre désignation: APLP1 (APLP1 Produits)

Sujet: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.,APLP1,APLP,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,APLP1

Poids moléculaire: 72 kDa

ID gène: 333

UniProt: P51693

Pathways: cAMP Metabolic Process