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ARHGAP44 anticorps (AA 666-772)

ARHGAP44 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6137082
  • Antigène Voir toutes ARHGAP44 Anticorps
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    Épitope
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 666-772
    Reactivité
    • 22
    • 6
    • 5
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ARHGAP44 est non-conjugé
    Application
    • 21
    • 17
    • 15
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).
    Isotype
    IgG
    Top Product
    Discover our top product ARHGAP44 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    Autre désignation
    ARHGAP44 (ARHGAP44 Produits)
    Synonymes
    anticorps RICH2, anticorps arhgap44, anticorps NPC-A-10, anticorps 6330543G20, anticorps AI840762, anticorps AU040829, anticorps AW493732, anticorps Rich2, anticorps Rho GTPase activating protein 44, anticorps si:ch211-114m9.1, anticorps ARHGAP44, anticorps si:ch211-114m9.1, anticorps Arhgap44
    Sujet
    GTPase-activating protein (GAP that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (By similarity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (By similarity. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity.,ARHGAP44,NPC-A-10,RICH2,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP44
    Poids moléculaire
    83 kDa/88 kDa/89 kDa
    ID gène
    9912
    UniProt
    Q17R89
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