BMP15 anticorps (AA 143-392)

N° du produit ABIN6137593

Détail du produit anti-BMP15 anticorps

Antigène: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Épitope: AA 143-392

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP15 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: LTRFNLSCHV EPWVQKNPTN HFPSSEGDSS KPSLMSNAWK EMDITQLVQQ RFWNNKGHRI LRLRFMCQQQ KDSGGLELWH GTSSLDIAFL LLYFNDTHKS IRKAKFLPRG MEEFMERESL LRRTRQADGI SAEVTASSSK HSGPENNQCS LHPFQISFRQ LGWDHWIIAP PFYTPNYCKG TCLRVLRDGL NSPNHAIIQN LINQLVDQSV PRPSCVPYKY VPISVLMIEA NGSILYKEYE GMIAESCTCR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human BMP15 (NP_005439.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BMP15

Antigène: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Autre désignation: BMP15 (BMP15 Produits)

Sujet: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.,BMP15,GDF9B,ODG2,POF4,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Germline Stem Cells,Cardiovascular,Angiogenesis,BMP15

Poids moléculaire: 45 kDa

ID gène: 9210

UniProt: O95972