BNIP3 anticorps (AA 1-164)

N° du produit ABIN6137620

Détail du produit anti-BNIP3 anticorps

Antigène: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Épitope: AA 1-164

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BNIP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MGDAAADPPG PALPCEFLRP GCGAPLSPGA QLGRGAPTSA FPPPAAEAHP AARRGLRSPQ LPSGAMSQNG APGMQEESLQ GSWVELHFSN NGNGGSVPAS VSIYNGDMEK ILLDAQHESG RSSSKSSHCD SPPRSQTPQD TNRASETDTH SIGEKNSSQS EEDD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human BNIP3 (NP_004043.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-BNIP3 (ABIN6137620)

Chen, Li, Li, Feng, Liu, Wang, Dai, Xia, Lu, Zhou, Guo: "15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy." dans: Acta pharmacologica Sinica, Vol. 38, Issue 5, pp. 672-687, (2018) (PubMed).

Zhang, Liu, Xue, Ma, Liu, Li, Li, Liu: "Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p." dans: Frontiers in molecular neuroscience, Vol. 11, pp. 92, (2018) (PubMed).

Détails sur BNIP3

Antigène: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Autre désignation: BNIP3 (BNIP3 Produits)

Synonymes: anticorps NIP3, anticorps Nip3, anticorps BCL2 interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3, anticorps BNIP3, anticorps Bnip3

Sujet: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.,BNIP3,NIP3,Cancer,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Hypoxia,Heart,Mitochondrial Control of Autophagy,BNIP3

Poids moléculaire: 27 kDa

ID gène: 664

UniProt: Q12983

Pathways: Autophagy, Brown Fat Cell Differentiation