C10orf2 anticorps (C-Term)

N° du produit ABIN6137714

Détail du produit anti-C10orf2 anticorps

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C10orf2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KRYLQVSKNR FDGDVGVFPL EFNKNSLTFS IPPKNKARLK KIKDDTGPVA KKPSSGKKGA TTQNSEICSG QAPTPDQPDT SKRSK

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human C10orf2 (NP_068602.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C10orf2

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Autre désignation: TWNK (C10ORF2 Produits)

Synonymes: anticorps ATXN8, anticorps IOSCA, anticorps MTDPS7, anticorps PEO, anticorps PEO1, anticorps PEOA3, anticorps SANDO, anticorps SCA8, anticorps TWINL, anticorps C6H10orf2, anticorps D19Ertd626e, anticorps Twinl, anticorps twinkle mtDNA helicase L homeolog, anticorps twinkle mtDNA helicase, anticorps twnk.L, anticorps TWNK, anticorps Twnk

Sujet: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,TWNK,ATXN8,C10orf2,IOSCA,MTDPS7,PEO,PEO1,PEOA3,PRLTS5,SANDO,SCA8,TWINL,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,TWNK

Poids moléculaire: 60 kDa/66 kDa/77 kDa

ID gène: 56652

UniProt: Q96RR1