C1R anticorps (AA 466-705)

N° du produit ABIN6137761

Détail du produit anti-C1R anticorps

Antigène: C1R (Complement Component 1, R Subcomponent (C1R))

Épitope: AA 466-705

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1R est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: GGQKAKMGNF PWQVFTNIHG RGGGALLGDR WILTAAHTLY PKEHEAQSNA SLDVFLGHTN VEELMKLGNH PIRRVSVHPD YRQDESYNFE GDIALLELEN SVTLGPNLLP ICLPDNDTFY DLGLMGYVSG FGVMEEKIAH DLRFVRLPVA NPQACENWLR GKNRMDVFSQ NMFCAGHPSL KQDACQGDSG GVFAVRDPNT DRWVATGIVS WGIGCSRGYG FYTKVLNYVD WIKKEMEEED

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 466-705 of human C1R (NP_001724.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C1R

Antigène: C1R (Complement Component 1, R Subcomponent (C1R))

Autre désignation: C1R (C1R Produits)

Synonymes: anticorps C1R, anticorps MGC84776, anticorps MGC127774, anticorps c1rl, anticorps complement C1r, anticorps complement component 1, r subcomponent L homeolog, anticorps complement component 1, r subcomponent, anticorps C1R, anticorps C1r, anticorps c1r.L, anticorps c1r

Sujet: The classical complement pathway plays a major role in innate immunity against infection. This pathway is triggered by C1, a multimolecular complex composed of the recognition protein C1q and two serine proteases, C1r and C1s. Following the C1q recognition, C1r is autoactivated, and in turn activates C1s, which cleaves C4 and C2, the C1 substrates. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This protien recognizes full-length C1r chain and the cleaved B chain.,C1R,EDSPD1,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,C1R

Poids moléculaire: 80 kDa

ID gène: 715

UniProt: P00736

Pathways: Système du Complément