Cyclin E2 anticorps (AA 255-404)

N° du produit ABIN6138092

Détail du produit anti-Cyclin E2 anticorps

Antigène: Cyclin E2 (CCNE2)

Épitope: AA 255-404

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: ALKDAPKVLL PQYSQETFIQ IAQLLDLCIL AIDSLEFQYR ILTAAALCHF TSIEVVKKAS GLEWDSISEC VDWMVPFVNV VKSTSPVKLK TFKKIPMEDR HNIQTHTNYL AMLEEVNYIN TFRKGGQLSP VCNGGIMTPP KSTEKPPGKH

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 255-404 of human Cyclin E2 (NP_477097.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Cyclin E2 (ABIN6138092)

Wu, Fu, Liu, Li, Huang, Xue, Xu, Sun, Zhao, Mi: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." dans: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: CCNE2 (CCNE2 Produits)

Synonymes: anticorps ccne2, anticorps MGC53684, anticorps MGC132360, anticorps cb165, anticorps sb:cb165, anticorps zgc:86724, anticorps CCNE2, anticorps cyce2, anticorps CYCE2, anticorps cyclin E2, anticorps cyclin E2 L homeolog, anticorps cyclin E1 L homeolog, anticorps CCNE2, anticorps ccne2.L, anticorps ccne2, anticorps ccne1.L, anticorps Ccne2

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.,CCNE2,CYCE2,cyclin E2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,CCNE2

Poids moléculaire: 41 kDa/46 kDa

ID gène: 9134

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases