CEMIP anticorps (AA 180-420)

N° du produit ABIN6138403

Détail du produit anti-CEMIP anticorps

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Épitope: AA 180-420

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEMIP est non-conjugé

Application: Western Blotting (WB)

Séquence: FERSWGHRGV IVHVIDPKSG TVIHSDRFDT YRSKKESERL VQYLNAVPDG RILSVAVNDE GSRNLDDMAR KAMTKLGSKH FLHLGFRHPW SFLTVKGNPS SSVEDHIEYH GHRGSAAARV FKLFQTEHGE YFNVSLSSEW VQDVEWTEWF DHDKVSQTKG GEKISDLWKA HPGKICNRPI DIQATTMDGV NLSTEVVYKK GQDYRFACYD RGRACRSYRV RFLCGKPVRP KLTVTIDTNV N

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 180-420 of human CEMIP (NP_061159.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CEMIP

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Autre désignation: CEMIP (CEMIP Produits)

Synonymes: anticorps CCSP1, anticorps TMEM2L, anticorps 3110012M15Rik, anticorps mKIAA1412, anticorps 12H19.01.T7, anticorps 6330404C01Rik, anticorps AY007814, anticorps Kiaa1199, anticorps KIAA1199, anticorps cell migration inducing hyaluronan binding protein, anticorps transmembrane protein 2, anticorps cell migration inducing protein, hyaluronan binding, anticorps CEMIP, anticorps Tmem2, anticorps TMEM2, anticorps Cemip

Sujet: Mediates depolymerization of hyaluronic acid (HA via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT, and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.,CEMIP,CCSP1,HYBID,KIAA1199,TMEM2L,Cancer,Tumor suppressors,Neuroscience,CEMIP

Poids moléculaire: 110 kDa/152 kDa

ID gène: 57214

UniProt: Q8WUJ3