CENPJ anticorps (AA 1069-1338)

N° du produit ABIN6138409

Détail du produit anti-CENPJ anticorps

Antigène: CENPJ (Centromere Protein J (CENPJ))

Épitope: AA 1069-1338

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPJ est non-conjugé

Application: Western Blotting (WB)

Séquence: DKLANTSVRF QNSQISSGTQ VEKYKKNYLP MQGNPPRRSK SAPPRDLGNL DKGQAASPRE PLEPLNFPDP EYKEEEEDQD IQGEISHPDG KVEKVYKNGC RVILFPNGTR KEVSADGKTI TVTFFNGDVK QVMPDQRVIY YYAAAQTTHT TYPEGLEVLH FSSGQIEKHY PDGRKEITFP DQTVKNLFPD GQEESIFPDG TIVRVQRDGN KLIEFNNGQR ELHTAQFKRR EYPDGTVKTV YANGHQETKY RSGRIRVKDK EGNVLMDTEL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1069-1338 of human CENPJ (NP_060921.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CENPJ

Antigène: CENPJ (Centromere Protein J (CENPJ))

Autre désignation: CENPJ (CENPJ Produits)

Synonymes: anticorps CENPJ, anticorps fi46g11, anticorps wu:fi46g11, anticorps si:dkey-46k9.9, anticorps BM032, anticorps CENP-J, anticorps CPAP, anticorps LAP, anticorps LIP1, anticorps MCPH6, anticorps SASS4, anticorps SCKL4, anticorps Sas-4, anticorps 4932437H03Rik, anticorps Gm81, anticorps centromere protein J, anticorps Cenpj, anticorps CENPJ, anticorps cenpj

Sujet: This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.,CENPJ,BM032,CENP-J,CPAP,LAP,LIP1,MCPH6,SASS4,SCKL4,Sas-4,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Centromere,CENPJ

Poids moléculaire: 124 kDa/153 kDa

ID gène: 55835

UniProt: Q9HC77

Pathways: M Phase